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pentobarbital will minimize the extent or effect of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic result of elbasvir/grazoprevir may very well be diminished if coadministered with powerful CYP3A inducers and it is thus contraindicated.pentobarbital will lower the extent or influenc